St. Luke's Hospital is at the forefront of osteoporosis treatment. Our goal is to promote bone health, reduce the risk of fracture, accelerate healing and prevent new fractures. The Osteoporosis Clinic ensures that every patient aged 50 years and above, who comes to the Clinic with a fracture, undergoes an osteoporosis evaluation. Although there is no cure for osteoporosis, there are steps that can prevent, slow down or stop its progress. In some cases, bone density may even improve to some extent. So, depending on the case, we help patients manage the disease and enjoy an active lifestyle.
For many decades osteoporosis was considered a "menopause disease". Now, thanks to early prevention, we know that more and more young women come up against this the disease due to various reasons such as premature menopause or treatment with antioestrogens due to breast cancer.
Osteoporosis is a chronic systemic disease, characterized by:
The above cause bones to become weak and brittle, increasing the likelihood of fracture. This probability increases even after minor injuries or simple, daily movements.
In other words, Osteoporosis makes bones weaker and prone to fractures.
Globally, 1 in 3 women and 1 in 5 men over the age of 50 will experience an osteoporotic fracture. Every year, it is estimated that about 1,660,000 million femoral head fractures take place, while it is estimated that, by the year 2050, this number will have quadrupled, due to an increase in life expectancy.
Prone to fractures are:
Fractures of the vertebrae can remain for years silent and occur in the form of progressive kyphosis (hump), accompanied by chronic pains and difficulties in mobility.
The aetiology of Osteoporosis is multifactorial. Bone mass increases in childhood and young adulthood through a complex process of absorption and reconstruction, reaching the maximum value at the age of 20-25 years (peak bone mass).
From the age of 35, the normal loss of bone mass begins, as more bone is absorbed than it is created.
The sharp menopausal drop in oestrogen levels makes women particularly vulnerable, while a variety of other genetic, hormonal, metabolic and exogenous factors seem to have a dynamic impact on bone reconstruction processes.
The diagnosis of Osteoporosis is made by measuring bone density, with the help of the dual energy X-ray Absorptiometry DXA measurement of X-rays and is completed by measuring biochemical and hormonal parameters of bone metabolism in the blood and/or urine.
The diagnostic algorithm is based on the results of biochemical and imaging tests and is modified based on the clinical picture and the patient's history.
Particular emphasis is placed on calculating the risk of falling with the help of clinical tests, as well as on assessing the total fracture risk with special tools (FRAX). Based on these results, a risk profile of the patient will be outlined, which will lay the foundation for an individualised counselling and therapeutic approach.
The treatment of Osteoporosis is based on:
Today, we have can provide the patient with a wide variety of medicines, which act:
There is also a new class of medicines with a double mechanism of action (monoclonal antibodies with binding and inhibition of sclerostin).
The Osteoporosis Clinic covers the entire diagnostic and therapeutic range of diseases of bone metabolism, with particular emphasis on the prevention, early and valid diagnosis and treatment of Osteoporosis.
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